Roles of Replication Protein A (RPA) in DNA Metabolism
DOI:
https://doi.org/10.31033/ijemr.10.6.20Keywords:
RPA, Single-Stranded DNA-Binding Protein, DNA Replication, Recombination, DNA Repair, Phosphorylation, Regulation of TranscriptionAbstract
Replication protein A (RPA) is a single-stranded binding protein. RPA homologues have been identified in all eukaryotic organisms examined and are all abundant heterotrimeric proteins composed of subunits of approximately 70, 30, and 14 kDa. RPA required in DNA metabolism including DNA repair, recombination and DNA replication When RPA is bound to single- stranded DNA, it is phosphorylated by DNA- dependent protein kinase.
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Copyright (c) 2020 Narendra Kumar, Anamica, Everest Shiwach, Sandeep Kumar, Suman Verma
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Research Articles in 'International Journal of Engineering and Management Research' are Open Access articles published under the Creative Commons CC BY License Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/. This license allows you to share – copy and redistribute the material in any medium or format. Adapt – remix, transform, and build upon the material for any purpose, even commercially.
