Roles of Replication Protein A (RPA) in DNA Metabolism

Narendra Kumar; Anamica; Everest Shiwach; Sandeep Kumar; Suman Verma

doi:10.31033/ijemr.10.6.20

Roles of Replication Protein A (RPA) in DNA Metabolism

Authors

Narendra Kumar Department of Botany, Meerut College, Meerut, UP, INDIA
Anamica Department of Botany, Meerut College, Meerut, UP, INDIA
Everest Shiwach Department of Botany, Deva Nagri College, Meerut, INDIA
Sandeep Kumar Department of Botany, Meerut College, Meerut, UP, INDIA
Suman Verma Department of Botany, Meerut College, Meerut, UP, INDIA

DOI:

https://doi.org/10.31033/ijemr.10.6.20

Keywords:

RPA, Single-Stranded DNA-Binding Protein, DNA Replication, Recombination, DNA Repair, Phosphorylation, Regulation of Transcription

Abstract

Replication protein A (RPA) is a single-stranded binding protein. RPA homologues have been identified in all eukaryotic organisms examined and are all abundant heterotrimeric proteins composed of subunits of approximately 70, 30, and 14 kDa. RPA required in DNA metabolism including DNA repair, recombination and DNA replication When RPA is bound to single- stranded DNA, it is phosphorylated by DNA- dependent protein kinase.

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Published

2020-12-31

How to Cite

Narendra Kumar, Anamica, Everest Shiwach, Sandeep Kumar, & Suman Verma. (2020). Roles of Replication Protein A (RPA) in DNA Metabolism. International Journal of Engineering and Management Research, 10(6), 144–149. https://doi.org/10.31033/ijemr.10.6.20